Comparison of Outcomes in Adults With Pediatric-Onset Morphea and Those With Adult-Onset Morphea: A Cross-Sectional Study From the Morphea in Adults and Children Cohort

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An evaluation of long-term outcomes in adults with pediatric-onset morphea.

T he prevalence of morphea in childhood is not well established, but reports suggest that approximately two-thirds of linear morphea cases occur before age 18 years, and 20% to 30% of morphea cases overall begin in childhood. Studies have described substantial morbidity in children with morphea, but to our knowledge none has addressed the disease effects when the patients reach adulthood (age 1...

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Fasciitis associated with generalized morphea.

Figure 1. Photograph of the legs. A large, thickened, firm, hyper/hypopigmented plaque is evident on the left leg. Figure 2. Biopsies of affected skin (A) and contiguous tibialis anterior muscle and fascia from the left leg (B–D). (A) The der-mal collagen is thickened, packed, and hyalinized. The subcutaneous fat is extensively replaced by collagen, and perivascular inflammatory infiltrates are...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatology

سال: 2014

ISSN: 2326-5191

DOI: 10.1002/art.38853